Vitamin D and Bone Health | Tables & Figures
Richard W. Reese, M.D.
Vitamin D deficiency is increasing in the U.S., and osteoporosis is so common, it’s considered inevitable, but these interlinked problems are avoidable. This comprehensive article details current guidelines for their management.

Fragility Fractures in the Osteoporotic Patient: Special Challenges
J. Paul Lyet, M.D., Ph.D.
Technical advances in the surgical treatment of fragility fractures have overcome many challenges. Still, one osteoporotic fracture means others are more likely. Education of patients, and long-term, multi-disciplinary treatment, are vital.

Vitamin D and the Heart
Roy S. Small, M.D., F.A.C.C.
Vitamin D appears to have multi-faceted cardiac effects, and to interact with an array of cardiac drugs. Yet, the evidence for its benefits is preliminary, and its therapeutic value for specific conditions is still unknown.

Vitamin D Metabolism In Chronic Kidney Disease: A Link Between Bone and Cardiovascular Disease
Laurence E. Carroll, M.D., F.A.S.N.
In chronic kidney disease, vitamin D supplements offer a lot of benefit for so little cost: they reverse secondary hyperparathyroidism, and reduce metabolic bone disease, vascular calcification, and the risk of cardiovascular events.

Osteoporosis and Prostate Cancer
Paul R. Sieber, M.D., F.A.C.S.
Men with prostate cancer often have prior osteoporosis, which cancer therapy can worsen. Metastases to weakened bone add another layer of difficulty. Drugs that lower testosterone levels while building bone are sorely needed.

Vitamin D and Mood Disorders
Peggy Nepps, Psy.D.
Depression and vitamin D deficiency are both becoming more common, and are linked in some studies. SAD occurs when exposure to sunlight is lowest. Does vitamin D play an important role in mood disorders?

From the Editor's Desk
You Ain't Seen Nothin' Yet!
Lawrence I. Bonchek, M.D., F.A.C.S., F.A.C.C.

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Out of The Hospital, But Not Out of Touch!
Jan Bergen

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